Veteran bullpen advice needed PLEASE, I am lost with setting

[sleepdok]

1)How are set-up men used in strat? If you designate set-up men, do they only come in in the middle innings if you are in the lead? If so, are they not used if the game is tied or if you are trailing?
2)Is it better to leave the set up man thing blank and let strat decide?
3)Is it generally better to have righty set up men that do better against righties , like 3R righties, or is it better to have reverse righties (and ditto for LHP.)
4)Is it generally better to have reverse relief pitchers in general?
5)How do you maximize closer usage with 1 closer without making him "tired" by pitching too many games in a row? am assuming by slow hooking some ot the starters?
6)How does HAL handle pitching changes? Say it's the 7th inning and a LHP, who has avoid rh hitters is brought in to face a lefty hitter. The left hand hitter has avoid LHP on his card. Assuming the LH hitter is pinch hit for, does the LHP now have to face the right hand hiiter?

Any other pertinent input on these confusing issues (at least for me) would be greatly appreciated!!!!!

[sleepdok]

excellent. thanks!