Here's one for agony:
http://fantasygames.sportingnews.com/baseball/stratomatic/2007/league/boxscore.html?group_id=6868&g_id=382
With a 9-4 lead going into the top of the 9th and my league-leading closer (Hoffman) on the mound, I give up 13 runs to lose 9-17.
Aaaaargh!!!