I find it challenging to put a lineup out there that is the best lineup for a three-game series, rather than a single game. I understand it's more realistic to have a per-game lineup that can be tweaked for each game, but, I'm okay with not being able to manage a per-game lineup.
Now, if you get to the finals and find that you play one or two games per night, that's also interesting. Start Gary Nolan in game 7 of the finals, but, pull him at 9:58 p.m for Nino Espinosa. Warning: Your opponent might not bat a reverse lineup because he is too lazy to change it from the previous day, so, do not try this strategy against lazy managers.