Speed is more difficult to come by in 20xx
But if you are able to get the speed guys it can be more effective strategy because not every team will have a -3 or better catcher to shut you down. There are so many great catchers in ATG that there is no reason to settle for a catcher who cannot throw runners out. Fewer catchers in 20xx mean several teams will go with good bat weak arm catchers allowing your speed based team to be more effective.
The other thing about playing 20xx is to jump in with multiple teams soon after the new game is released. In any player set there are value guys who get underpriced if used properly in the right parks. Or cards that simply over or under perform from what you would expect just looking at or counting the card. In ATG where the pool is static these are well known to everyone. In 20xx where the entire set changes each year those jumping in early learn these value cards more quickly than the person who just plays a team at a time or waits until mid-summer to field a 20xx team.
Also, in ATG you probably have the set memorized. If I call out a name you can probably tell me if that guy is a platoon guy, prefers LH or RH pitching, if he needs platooning, etc. In 200x with all new cards Teixeira might be 4L one year and 4R the next. That does not come in to play so much in filling out your draft card. But when reacting to a frenzy situation the difference between knowing by memory who is probably available and best for any situation and having to examine the FA list and cards could be the difference in getting the right fit or being left out in the cold. Remember the pool is smaller and more limited which magnifies this effect. Miss on your first choice, be indecisive on selecting your alternative so someone else gets it and there may not be anything worth having left at that position who fits your need.
Another thing about the pool changing every year. One year there may be a lot of choices for a bomber team while another might have limited choices. Ditto for basestealers. One year they may be plentiful and the next pickings may be slim. So more flexibility is needed on your part to adjust your strategy to fit the pool. The larger pool in ATG means whatever strategy you want to pursue you have many options. In 20xx the pool may to some extent dictate or limit your strategy choices. My own stubbornness on team building worked against me in some 20xx years.